CEREBROSPINAL-FLUID CYTOMORPHOLOGIC FINDINGS IN 41 INTRACRANIAL TUMORS - A RETROSPECTIVE REVIEW

• Type: Another Publication in an International Scientific Journal
• Date: 1995

Authors

SA, MJ (Author) Other; VAZ, R (Author) Other; CRUZ, C (Author) Other

Journal

Title: Arquivos de Neuro-Psiquiatria

Vol. 53

Pages: 218-226

ISSN: 0004-282X

Publisher: Associacao Arquivos de Neuro-Psiquiatria Dr. Oswaldo Lange

Indexing

ISI Web of Knowledge - 7 Citations

Scopus - 8 Citations

Other information

Authenticus ID: P-001-GS7

Abstract (EN): The main objective of this retrospective review of clinical and cerebrospinal fluid (CSF) data from 41 patients with intracranial tumors diagnosed between 1975 and 1989, is to report the role that the finding of neoplastic cells in CSF plays, specially when cerebral CT-scanning and MRI were not currently done. Another objective is to study the CSF proteic abnormalities in cerebral tumors. CSF cell count, cytomorphologic pictures obtained after sedimentation and protein findings are described. Tumor cells were seen in 12 cases (29%): medulloblastomas -6, meningeal carcinomatosis - 3, multiforme glioblastoma - 1, ependymoma - 1, cerebral metastasis - 1; in two cases it was an unexpected finding. We noticed that tumoral localization next to the ventricles favoured cell exfoliation. Although pleocytosis was rare and uncorrelated with the presence of neoplastic cells, pathological cytomorphologic pictures appeared in most of the cases including all ''positive'' ones. Our results stress that the appearance of neoplastic cells in CSF remains helpful specially when it is an unexpected finding.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9