Recurrent wells' syndrome associated with allergic asthma exacerbation

• Type: Article in International Scientific Journal
• Date: 2012

Authors

Cruz, MJ (Author) Other; Alberto Mota (Author) FMUP; Baudrier, T (Author) Other; Guimaraes, S (Author) Other; Azevedo, F (Author) Other

Journal

Title: Cutaneous and Ocular Toxicology

Vol. 31

Pages: 154-156

ISSN: 1556-9527

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 3 Citations

Scopus - 3 Citations

Other information

Authenticus ID: P-002-9PQ

DOI: 10.3109/15569527.2011.627523

Abstract (EN): Wells syndrome is an inflammatory eosinophilic dermatosis of unknown pathogenesis characterized by clinical polymorphism, a suggestive but nonspecific histopathologic traits, usually with a recurrent course and inconstant response to therapy. It seems to be an unspecific hypersensitivity reaction in response to various exogenous and endogenous stimuli, such as insect bites, infections, drug eruption or underlying internal disorders. We present a patient with allergic asthma and atopic dermatitis in whom a skin eruption developed in the sequence of allergic asthma exacerbation, which was clinically and histologically consistent with the diagnosis of eosinophilic cellulitis. The authors discuss the probability of a common pathogenesis and the role of IL-5. To our best knowledge this is the first pediatric case where this association is reported.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3