Surveillance of patients with gastric precancerous conditions

• Type: Article in International Scientific Journal
• Date: 2016

Authors

Lage, J (Author) Other; Uedo, N (Author) Other; Mario Dinis Ribeiro (Author) FMUP; Yao, K (Author) Other

Journal

Title: Best Practice and Research in Clinical Gastroenterology

Vol. 30

Pages: 913-922

ISSN: 1521-6918

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 15 Citations

Other information

Authenticus ID: P-00M-BQ2

DOI: 10.1016/j.bpg.2016.09.004

Abstract (EN): Intestinal-type gastric adenocarcinoma arises from a multistep process starting with Helicobacter pylori infection followed by gastric atrophy, gastric intestinal metaplasia and dysplasia. Indeed, patients with gastric precancerous conditions or lesions (GPC) are at increased risk to develop gastric cancer even in regions with low incidence. Thus, the identification and surveillance of a high risk subgroup could lead to the diagnosis of cancer at early stage and improve survival. However, both endoscopic and histological accuracy and interobserver agreement in the diagnosis of GPC are still far from optimal. Also, there are conceptual differences between the West and the East in the diagnosis and surveillance of patients. In the former, multiple gastric biopsies are still recommended but Eastern gastroenterologists select patients to surveillance according to the results of endoscopy or serology. In this literature review we describe the cascade of GPC and we highlight the differences between eastern and western clinical practice.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10