Dietary glycemic load and its association with glucose metabolism and lipid profile in young adults

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Fernandes, AC (Author) Other; Marinho, AR (Author) Other; Lopes C (Author) FMUP; Ramos, E (Author) Other

Journal

Title: Nutrition, Metabolism and Cardiovascular Diseases

Vol. 32

Pages: 125-133

ISSN: 0939-4753

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 6 Citations

Other information

Authenticus ID: P-00V-V15

DOI: 10.1016/j.numecd.2021.10.001

Abstract (EN): Background and aim: To evaluate the association of Glycemic Load (GL) with glucose metabolism and blood lipids among young adults. Methods and results: This study included 1538 participants (51% females), evaluated at 21 years of age as part of the EPITeen cohort. The GL of each individual was obtained from the assessment of their dietary intake by using a 86-item semi-quantitative food frequency questionnaire. The eval-uation included anthropometric measurements and a fasting blood sample was used to measure glucose, insulin, triglycerides, total cholesterol, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Insulin resistance was calculated based on the ho-meostasis model method (HOMA-IR). The association between the GL and the biochemical pa-rameters was evaluated by linear regression models using 13 and 95% confidence intervals (95% CI), stratified by sex and adjusted for body mass index (BMI), energy and fiber intake, and self-perceived social class. No association was found between GL and the glucose metabolism pa-rameters after adjustment. Regarding blood lipids, a positive association was found with LDL-C (13 = 1.507, 95% CI 0.454; 2.561 for females; 13 = 0.216, 95% CI-0.587; 1.020 for males) and a negative association with HDL-C (13 =-0.647, 95% CI-1.112;-0.181 for females; 13 =-0.131, 95% CI-0.422; 0.160 for males). Conclusions: Our results suggest that, in healthy young subjects, a high GL diet may have a nega-tive impact on lipid profile.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9