Treatment and Other Healthcare Use of Breast Cancer Patients With a Previous Cancer Diagnosis

• Type: Article in International Scientific Journal
• Date: 2020

Authors

Morais, S (Author) FMUP; Costa, AR (Author) Other; Lopes Conceicao, L (Author) Other; Brandao, M (Author) Other; Borges, M (Author) Other; Araujo, N (Author) Other; Dias, T (Author) Other; Fontes, F (Author) FMUP; Pereira, S (Author) Other; Lunet N (Author) FMUP

Journal

Title: Anticancer Research

Vol. 40

Pages: 1041-1048

ISSN: 0250-7005

Publisher: International Institute of Anticancer Research

Indexing

ISI Web of Knowledge - 2 Citations

Scopus - 2 Citations

Other information

Authenticus ID: P-00R-PJ4

DOI: 10.21873/anticanres.14040

Abstract (EN): Background/Aim: To quantify the association between a previous cancer diagnosis and healthcare use among breast cancer (BC) patients, and estimate five-year recurrence-free survival (RFS). Patients and Methods: Women with BC were classified according to a previous cancer diagnosis (BC or other). Healthcare use during the first year and five-year RFS were obtained through clinical and administrative records. Adjusted odds ratios and hazard ratios (HR) were estimated. Results: Among 681 BC patients, 21 had a previous BC and 32 a previous non-BC. The latter were less likely to receive anthracycline-based combination chemotherapy. The former had higher odds of mastectomy and genetic testing. Five-year RFS HRs (95% confidence interval) were 2.75 (0.79-9.52) and 0.52 (0.07-3.89) for previous BC and non-BC, respectively. Conclusion: Previous cancer was associated with less anthracycline-based combination chemotherapy, and patients were more likely to undergo mastectomy and genetic testing. These findings highlight the need for assessment of previous treatments, personal genetic risk and current BC characteristics.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8