PROCESS INTEGRATION INVOLVING LIPASE-CATALYZED ESTER SYNTHESIS REACTIONS

• Type: Article in International Scientific Journal
• Date: 1994

Authors

PAIVA, AL (Author) Other; F. Xavier Malcata (Author) Other

Journal

Title: Biotechnology Techniques

Vol. 8

Pages: 629-634

ISSN: 0951-208X

Publisher: Kluwer Academic Publishers

Indexing

ISI Web of Knowledge - 13 Citations

Scopus - 12 Citations

Other information

Authenticus ID: P-001-JMJ

Abstract (EN): The technical feasibility of integrating bioconversion (using a lipase from Mucor miehei immobilized by ion exchange onto a macroporous resin) and product recovery (via mass transfer towards Liquid/vapor equilibrium) was experimentally verified for the production of ethyl acetate from acetic acid and ethanol at 30 and 40 degrees C. The configuration selected consisted of a packed bed thermostatted reactor inserted between the condenser and the liquid reflux to a distillation column. The concentrations of the aforementioned components and water were measured periodically for a 9 to 10-h period. The extents of conversion of acetic acid ranged from 1 to 32% at 30 degrees C, and from 13 to 25% at 40 degrees C, and they were maximum at initial molar fractions of acid of ca. 0.3 and 0.4, respectively. The ratio of the reaction product to the equilibrium reaction product increased from 2 to 32 at 30 degrees C, and from 5 to 27 at 40 degrees C when the initial molar fraction of acid in the feed increased from 0.2 to 0.7.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6