Kinetics of lipase-mediated synthesis of butyl butyrate in n-hexane

• Type: Article in International Scientific Journal
• Date: 2002

Authors

Paiva, AL (Author) Other; van Rossum, D (Author) Other; F. Xavier Malcata (Author) Other

Journal

Title: Biocatalysis and Biotransformation

Vol. 20

Pages: 43-51

ISSN: 1024-2422

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 16 Citations

Other information

Authenticus ID: P-000-QBR

DOI: 10.1080/10242420290003254

Abstract (EN): This paper reports experimental and modeling work concerning alcoholysis reactions between butanol and ethyl butanoate, catalyzed by Lipozyme(TM) in n-hexane, using a batch stirred system at 60degreesC. Description of the reaction kinetics was based on a postulated multisubstrate Ping Pong Bi Bi mechanism, and appropriate rate expressions were derived for all components in the reaction medium. Simplified models were fitted by non-linear multiresponse regression analysis to data (experimental or calculated from mass balances, as appropriate) encompassing the concentrations of free butanol, ethyl butanoate, ethanol and butyl butanoate. Finally, incremental F-tests were performed to assess the simplest model form that was able to provide a statistically good fit throughout the entire reaction time frame.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9