Could condensin scaffold the mitotic chromosome?

• Type: Another Publication in an International Scientific Journal
• Date: 2004

Authors

Coelho, PA (Author) Other; Queiroz Machado, J (Author) Other; Sunkel, CE (Author) ICBAS

Journal

Title: Cell Cycle

Vol. 3

Pages: 536-538

ISSN: 1538-4101

Publisher: Taylor & Francis

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-00R-MX0

Abstract (EN): One of the most remarkable and yet poorly understood events during the cell cycle is how dispersed chromatin fragments are transformed into chromosomes every time cells undergo mitosis. It has been postulated that mitotic chromosomes might contain an axial scaffold that is involved in condensation but its molecules and structure have remained elusive. Recent data suggests that the condensin complex might indeed be an essential part of the scaffold that provides a platform for other proteins to localize and promote different aspects of chromosome condensation.

Language: English

Type (Professor's evaluation): Scientific