Short and Medium-term Outcomes of Omphalocele and Gastroschisis: A Survey from a Tertiary Center

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Estevão-Costa J (Author) FMUP; Marques AT (Author) Other; Henrique Soares (Author) FMUP; Fragoso AC (Author) FMUP

Journal

The Journal is awaiting validation by the Administrative Services.

Title: REVISTA BRASILEIRA DE GINECOLOGIA E OBSTETRICIA

Vol. 44

Pages: 10-18

ISSN: 0100-7203

Indexing

ISI Web of Knowledge - 3 Citations

Scopus - 2 Citations

Pubmed / Medline

Scientific classification

CORDIS: Health sciences > Medical sciences

Other information

Authenticus ID: P-00W-1ER

DOI: 10.1055/s-0041-1736299

Abstract (EN): Objective To characterize and compare the outcomes of omphalocele and gastroschisis from birth to 2 years of follow-up in a recent cohort at a tertiary center. Methods This is a retrospective clinical record review of all patients with gastroschisis and omphalocele admitted to the Neonatal Intensive Care Unit between January 2009 and December 2019. Results There were 38 patients, 13 of whom had omphalocele, and 25 of whom had gastroschisis. Associated anomalies were present in 6 patients (46.2%) with omphalocele and in 10 (41.7%) patients with gastroschisis. Compared with patients with omphalocele, those with gastroschisis had younger mothers (24.7 versus 29.6 years; p = 0.033), were born earlier (36 versus 37 weeks, p = 0 .006 ), had lower birth weight (2365 +/- 430.4 versus 2944.2 +/- 571.9 g; p = 0.001), and had a longer hospital stay (24 versus 9 days, p = 0.001). The neonatal survival rate was 92.3% for omphalocele and 91.7% for gastroschisis. Thirty-four patients were followed-up over a median of 24 months; 13 patients with gastroschisis (59.1%) and 8 patients with omphalocele (66.7%) had at least one adverse event, mainly umbilical hernia (27.3% vs 41.7%), intestinal obstruction (31.8% vs 8.3%), or additional surgical interventions (27.3% vs 33.3%). Conclusion Despite the high proportion of prematurity, low birth weight, and protracted recovery, gastroschisis and omphalocele (without chromosomal abnormalities) may achieve very high survival rates; on the other hand, complications may develop in the first years of life. Thus, a very positive perspective in terms of survival should be transmitted to future parents, but they should also be informed that substantial morbidity may occur in the medium term.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9