Effects of high-intensity infrasound on liver lipid content of rats

• Type: Article in International Scientific Journal
• Date: 2020-06-29

Authors

Gonçalo Martins Pereira (Author) Other; Sofia S. Pereira (Author) ICBAS; Madalena santos (Author) ICBAS; José Brito (Author) Other; Diamantino Freitas (Author) FEUP; António Oliveira de Carvalho (Author) FEUP; Artur Águas (Author) ICBAS; Maria João Oliveira (Author) ICBAS; Pedro Oliveira (Author) Other

Journal

Title: Heliyon

Vol. 6

ISSN: 2405-8440

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 4 Citations

Scopus - 5 Citations

Other information

Authenticus ID: P-00S-DA7

DOI: 10.1016/j.heliyon.2020.e04383

Abstract (EN): Previous experimental studies show that exposure to noise with high and audible frequencies causes multiple metabolic alterations, such as increased liver glycogen and triglycerides. However, the effect of exposure to sound with lower frequencies, such as high-intensity infrasound (frequency 20 Hz and sound pressure level 90 dB), on the liver lipid content is still unclear. As such, we aimed to study the effect of exposure to high-intensity infrasound of both normal and glucose intolerant rats on the liver lipid content. For this study, 79 wild-type male Wistar rats were randomly divided into two groups: G1, no treatment, and G2, induced glucose intolerance. Each of these two groups was randomly divided in two subgroups: s (animals kept in silence) and i (animals continuously exposed to high-intensity infrasound noise). At three noise-exposure time-points (1, 6 and 12 weeks) the rats were sacrificed, the liver was excised and hepatic lipids extracted. Data analysis was performed using a two-way ANOVA (p = 0.05). No significant effects due to interactions between the several factors exist on the liver lipid content (p=0.077). Moreover, no significant effects due to infrasound exposure (p=0.407) or glucose tolerance status (p=0.938) were observed. Our study shows that continuous exposure to high-intensity infrasound has no influence on the lipid content of the liver of both normal and glucose intolerant animals. This finding reinforces the need for further experimental studies on the physiological effects of infrasound due to its possible hazardous effects on human health.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5