Probiotic Ingestion, Obesity, and Metabolic-Related Disorders: Results from NHANES, 1999-2014

• Type: Article in International Scientific Journal
• Date: 2019

Authors

Lau, E (Author) Other; Neves, JS (Author) FMUP; Ferreira Magalhaes, M (Author) Other; Carvalho, Davide (Author) FMUP; Freitas, P (Author) FMUP

Journal

Title: Nutrients

Vol. 11 No. 10

Final page: 1482

ISSN: 2072-6643

Publisher: MDPI

Indexing

ISI Web of Knowledge - 32 Citations

Scopus - 36 Citations

Other information

Authenticus ID: P-00Q-V9B

DOI: 10.3390/nu11071482

Abstract (EN): Gut microbiota dysbiosis has been recognized as having key importance in obesity- and metabolic-related diseases. Although there is increasing evidence of the potential benefits induced by probiotics in metabolic disturbances, there is a lack of large cross-sectional studies to assess population-based prevalence of probiotic intake and metabolic diseases. Our aim was to evaluate the association of probiotic ingestion with obesity, type 2 diabetes, hypertension, and dyslipidemia. A cross-sectional study was designed using data from the National Health and Nutrition Examination Survey (NHANES), 1999-2014. Probiotic ingestion was considered when a subject reported consumption of yogurt or a probiotic supplement during the 24-h dietary recall or during the Dietary Supplement Use 30-Day questionnaire. We included 38,802 adults and 13.1% reported probiotic ingestion. The prevalence of obesity and hypertension was lower in the probiotic group (obesity-adjusted Odds Ratio (OR): 0.84, 95% CI 0.76-0.92, p < 0.001; hypertension-adjusted OR: 0.79, 95% CI 0.71-0.88, p < 0.001). Accordingly, even after analytic adjustments, body mass index (BMI) was significantly lower in the probiotic group, as were systolic and diastolic blood pressure and triglycerides; high-density lipoprotein (HDL) was significantly higher in the probiotic group for the adjusted model. In this large-scale study, ingestion of probiotic supplements or yogurt was associated with a lower prevalence of obesity and hypertension.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 12