Towards effective COVID-19 vaccines: Updates, perspectives and challenges (Review)

• Type: Another Publication in an International Scientific Journal
• Date: 2020

Authors

Calina, D (Author) Other; Docea, AO (Author) Other; Petrakis, D (Author) Other; Egorov, AM (Author) Other; Ishmukhametov, AA (Author) Other; Gabibov, AG (Author) Other; Shtilman, MI (Author) Other; Kostoff, R (Author) Other; Felix Carvalho (Author) FFUP; Vinceti, M (Author) Other; Spandidos, DA (Author) Other; Tsatsakis, A (Author) Other

Journal

Title: International Journal of Molecular Medicine

Vol. 46

Pages: 3-16

ISSN: 1107-3756

Publisher: Demetrios A. Spandidos Ed. & Pub.

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 69 Citations

Other information

Authenticus ID: P-00S-4TK

DOI: 10.3892/ijmm.2020.4596

Abstract (EN): In the current context of the pandemic triggered by SARS-COV-2, the immunization of the population through vaccination is recognized as a public health priority. In the case of SARS-COV-2, the genetic sequencing was done quickly, in one month. Since then, worldwide research has focused on obtaining a vaccine. This has a major economic impact because new technological platforms and advanced genetic engineering procedures are required to obtain a COVID-19 vaccine. The most difficult scientific challenge for this future vaccine obtained in the laboratory is the proof of clinical safety and efficacy. The biggest challenge of manufacturing is the construction and validation of production platforms capable of making the vaccine on a large scale.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 14