Immunohistochemistry in the anatomopathologic diagnosis [Contribuição do estudo imuno-histoquímico para o diagnóstico anátomo-patológico.]

• Type: Article in International Scientific Journal
• Date: 1992

Authors

Fernando Schmitt (Author) Other; Kimaid, PA (Author) Other; Campos, PF (Author) Other; Bacchi, CE (Author) Other

Journal

Title: Revista do Hospital das Clinicas de Faculdade de Medicina da Universidade de Sao Paulo

Vol. 47

Pages: 1-5

ISSN: 0041-8781

Publisher: Universidade de São Paulo. Faculdade de Medicina

Indexing

Scopus - 1 Citation

Other information

Authenticus ID: P-008-PRE

Abstract (EN): In order to determine the value of immunohistochemical staining methods for morphologic diagnosis specimens of 949 cases received at the Immunohistochemistry Laboratory of the Department of Pathology of the Medical School of Botucatu, in the period 1984-1989 were reviewed. All of them were submitted to the immunoperoxidase staining (PAP or ABC). The main morphologic diagnosis was confirmed in 468 cases (49.3%); the definitive diagnosis was made in 244 cases (25.7%) that had only differential diagnosis, and contributory information was provided in 74 cases (7.8%); the immunohistochemical staining was non-contributory in 114 cases (12%). It rendered an unsuspected diagnosis in 49 cases (5.2%). The analysis of these cases shows that immunohistochemical methods may provide important and sometimes essential informations for definitive diagnosis. This technique is particularly useful for distinguishing between carcinoma, lymphoma and melanoma.

Language: Portuguese

Type (Professor's evaluation): Scientific