Benign and malignant apocrine lesions of the breast

• Type: Another Publication in an International Scientific Journal
• Date: 2012

Authors

Gerhard, R (Author) Other; Costa, JL (Author) Other; Fernando Schmitt (Author) FMUP

Journal

Title: Expert Review of Anticancer Therapy

Vol. 12

Pages: 215-221

ISSN: 1473-7140

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 7 Citations

Scopus - 9 Citations

Other information

Authenticus ID: P-002-DBW

DOI: 10.1586/era.11.213

Abstract (EN): Apocrine differentiation occurs in a variety of breast lesions, both benign and malignant. This review is a reflection of our critical view of the recent advances towards the understanding of this particular type of breast lesions. Focus is given to the histological criteria that allow their reproductive identification, with additional attention to the recent microarray studies. These describe the recent molecular classification of breast cancer and identify an apocrine molecular subtype that opens the door for new putative therapies for this particular type of tumor. Indeed we anticipate that the determination of androgen receptor will enter into the routine assessment of breast cancer cases and become a surrogate marker for treatment in apocrine triple-negative breast cancer.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7