Lactate-Induced IL-8 Pathway in Endothelial Cells-Letter

• Type: Another Publication in an International Scientific Journal
• Date: 2012

Authors

Pinheiro, C (Author) Other; Longatto Filho, A (Author) Other; Nogueira, R (Author) Other; Fernando Schmitt (Author) FMUP; Baltazar, F (Author) Other

Journal

The Journal is awaiting validation by the Administrative Services.

Title: CANCER RESEARCH

Vol. 72

Pages: 1901-1902

ISSN: 0008-5472

Indexing

ISI Web of Knowledge - 5 Citations

Scopus - 5 Citations

Other information

Authenticus ID: P-002-BGQ

DOI: 10.1158/0008-5472.can-11-1540

Abstract (EN): Vegran and colleagues proposed a model in which the lactate released from tumor cells through MCT4 would be taken up by endothelial cells via the MCT1 transporter and stimulate angiogenesis, using human umbilical vein endothelial cells (HUVECs) as model of tumor endothelial cells. By analyzing a total of 505 cases of human tumor samples immunostained for MCT1, we do not confirm plasma membrane expression of MCT1 in the endothelial cells of tumor-associated vessels. Cancer Res; 72(7); 1901-2. (C)2012 AACR.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 2