Changes in copper load in hepatocytes of Ohrid trout in relation to the ovarian maturation cycle

• Type: Article in International Scientific Journal
• Date: 2020

Authors

Jordanova, M (Author) Other; Rebok, K (Author) Other; rocha, e (Author) ICBAS; rocha, mj (Author) ICBAS

Journal

Title: Toxicological and Environmental Chemistry

Vol. 102

Pages: 272-283

ISSN: 0277-2248

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00S-F3G

DOI: 10.1080/02772248.2020.1781854

Abstract (EN): The main aim of this study was to histochemically estimate the relative copper content in the liver during the breeding cycle of female Ohrid trout, a wild population endemic to the Ohrid Lake. The histology of the oogenetic cycle in this species was documented for the first time. Histochemistry with semi-quantification revealed positive correlations between the gonadosomatic indices and copper load. Uptake of the metal increases in the liver as the ovaries increase in size, with the highest hepatic copper load occurring postspawning. The plasmatic levels of 17 beta-oestradiol were also quantified, but no correlations to copper load were found, so there is no direct estrogenic control on the uptake and release of copper from the bloodstream to either organ. Therefore, when interpreting field studies or assays on hepatic copper pollution and toxicity, breeding-related seasonal changes in Ohrid trout must be taken into account.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 12