Frailty phenotype and associated nutritional factors in a sample of Portuguese outpatients with heart failure

• Type: Article in International Scientific Journal
• Date: 2021

Authors

Valdiviesso, Rui (Author) FCNAUP; Azevedo L (Author) FMUP; Moreira, E (Author) FMUP; Ataíde, R (Author) Other; Martins, S (Author) FMUP; Lia Fernandes (Author) FMUP; Silva Cardoso, J (Author) FMUP; Borges, Nuno (Author) FCNAUP

Journal

Title: Nutrition, Metabolism and Cardiovascular Diseases

ISSN: 0939-4753

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 7 Citations

Scopus - 7 Citations

Scientific classification

CORDIS: Health sciences

FOS: Medical and Health sciences

Other information

Authenticus ID: P-00T-T1A

DOI: 10.1016/j.numecd.2021.03.028

Abstract (EN): Background and aim: Frailty phenotype (FP) is very common in heart failure (HF) and both syndromes worsen one another. The aim of this study is to first describe FP in a sample of Portuguese patients with HF, and to analyse its association with nutritional and clinical statuses, namely, muscle mass, obesity and functional class. Methods and results: In this cross-sectional study, a sample of 136 outpatients with HF (24¿81 years, 33.8% women) were randomly selected from the appointments' listings of a HF and Transplant clinic in a Portuguese University Hospital. FP was assessed according to Fried et al. muscle mass was estimated from the mid-upper arm muscle circumference; weight status was assessed using the body mass index; HF functional classes were registered. The association between participants' characteristics and FP categories was analysed using logistic ordinal regression. The frequency of pre-frailty and frailty is 57.4% and 15.4%, respectively. Within frail individuals, 52.4% were under the age of 65. In multivariable analysis, frailty was positively associated with age 70 or older (OR = 3.44) and obesity (OR = 2.66), and negatively associated with muscle mass (OR = 0.77) and HF functional classes I (OR = 0.14) or II (OR = 0.29). Conclusion: Muscle mass seems to be an important predictor of frailty in patients with HF and should be taken into account when designing intervention plans that allow for reverting or modifying frailty and pre-frailty. Younger patients should be monitored for the presence and evolution of FP. © 2021 The Authors

Language: English

Type (Professor's evaluation): Scientific