Retinal oxygen saturation as a non-invasive estimate for mixed venous oxygen saturation and cardiac output

• Type: Article in International Scientific Journal
• Date: 2019

Authors

Van Keer, K (Author) Other; Van Keer, J (Author) Other; Breda, JB (Author) FMUP; Nassiri, V (Author) Other; Van Cleemput, J (Author) Other; Pinto, LA (Author) Other; Stalmans, I (Author) Other; Vandewalle, E (Author) Other

Journal

Title: Acta Ophthalmologica

Vol. 97

Pages: E308-E312

ISSN: 1755-375X

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 3 Citations

Scopus - 3 Citations

Other information

Authenticus ID: P-00P-QVS

DOI: 10.1111/aos.13890

Abstract (EN): Purpose To investigate the correlation between retinal vessel oxygen saturation and mixed venous oxygen saturation (SvO(2-mixed)) and cardiac output (CO). Methods Retinal arterial (SaO(2-retinal)) and venous (SvO(2-retinal)) oxygen saturation were measured non-invasively with dual-wavelength retinal oximetry in subjects receiving invasive measurements of SvO(2-mixed) and CO through right heart catheterization. Correlations were analysed using Spearman's rank correlation coefficients and linear regression models. Results Fourteen patients (median age 62.7 years, range: 21-77) were included in the analysis. When adjusted for age, SvO(2-retinal) showed a positive correlation with SvO(2-mixed) (beta = 0.80, p = 0.003). Retinal arteriovenous oxygen saturation difference was significantly correlated with the inverse of CO (Spearman's rho = 0.59, p = 0.026). Conclusion This pilot study provides proof of concept for the use of retinal oximetry as a non-invasive tool to assess systemic cardiovascular function.

Language: English

Type (Professor's evaluation): Dissemination

No. of pages: 5