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Wound healing angiogenesis: An overview on mathematical models

Title
Wound healing angiogenesis: An overview on mathematical models
Type
Article in International Conference Proceedings Book
Year
2019
Authors
A. C. Guerra
(Author)
Other
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Jorge Belinha
(Author)
Other
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Renato Natal Jorge
(Author)
FEUP
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Conference proceedings International
Pages: 237-244
Proceedings of the 5th International Conference on Biodental Engineering (BIODENTAL 2018)
Porto, Portugal, June 22-23, 2018
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Authenticus ID: P-00Q-E0R
Abstract (EN): Angiogenesis, the formation of new blood vessels from pre-existent ones, is a fundamental process in wound healing since it allows the reestablishment of the normal blood flow and the sufficient exchange of oxygen and nutrients, essential for cell proliferation and viability. In the last three decades, computational mathematical modelling have been under focus due to its possibility to mimic biological processes and to test new therapies using non-invasive procedures. With this paper, we provided a global view of the current approaches to model wound healing angiogenesis, pointing out the advantages and disadvantages of using different mathematical models in order to identify possible improvements. The development of wound healing angiogenesis models with higher dimension and that incorporate multi-scale analysis remains a challenge.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 8
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