Current vs Emerging Natural Compounds-Based Treatments for Alzheimer’s Disease

• Type: Chapter or Part of a Book
• Date: 2021-03-01

Authors

Maria Ramalho (Author) FEUP; Stephanie Andrade (Author) Other; Meghna Dabur (Author) Other; Joana A. Loureiro (Author) FEUP; Maria do Carmo Pereira (Author) FEUP

Book

Title: Alzheimer's Disease & Treatment

Pages: 26-30

ISBN: 978-81-936678-7-3

Other information

Abstract (EN): Alzheimer’s disease is a progressive and irreversible neurodegenerative disease that affects millions of people globally. Presently, AD is considered a serious health concern, a social and economic burden. There is still no medically accepted cure for AD. Current therapeutics that are marketed for AD treatment only attenuate the symptoms and have several side effects. To avoid the side effects associated with synthetic drugs, natural compounds have gained huge attention in the last 20 years, since they have been part of our common diet and have shown neuroprotective effects. This chapter presents a brief review on the existing medication and ongoing research on natural compounds in clinical trials for AD treatment. However, natural compounds alone have low permeability through the Blood Brain Barrier (BBB) and have low bioavailability. Therefore, a combination of natural compounds with nanocarriers could be a potential therapeutic strategy for AD.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5