Intraocular Pressure and Anterior Segment Morphometry Changes after Uneventful Phacoemulsification in Type 2 Diabetic and Nondiabetic Patients

• Type: Article in International Scientific Journal
• Date: 2019

Authors

Beato, JN (Author) Other; Reis, D (Author) Other; Esteves Leandro, J (Author) Other; Manuel Falcão (Author) FMUP; Rosas, V (Author) Other; Ângela Carneiro (Author) FMUP; Falcão-Reis F (Author) FMUP

Journal

Title: Journal of Ophthalmology

Vol. 2019

Pages: 1-10

ISSN: 2090-004X

Publisher: Hindawi

Indexing

ISI Web of Knowledge - 6 Citations

Scopus - 4 Citations

Other information

Authenticus ID: P-00Q-S01

DOI: 10.1155/2019/9390586

Abstract (EN): Purpose. To compare intraocular pressure (IOP) and anterior segment (AS) morphometry changes after uneventful phacoemulsification between nonglaucomatous eyes with open-angles from patients with and without type 2 diabetes mellitus (DM) and determine which factors may predict greater IOP-lowering effect. Methods. Forty-five diabetic (45 eyes) and 44 (44 eyes) age- and sex-matched non-DM patients with age-related cataract were enrolled in this prospective observational study. Goldmann applanation tonometry and AS Scheimpflug tomography (Pentacam (R) HR) were performed preoperatively and at 1- and 6-month follow-up. Linear regression analysis was performed to evaluate the clinical variables related to postoperative IOP changes at 6months. Results. There was a significant postoperative IOP reduction 6months after surgery (p<0.001) by an average of 2.9 +/- 2.9mmHg (15.5%) and 2.4 +/- 2.8mmHg (13.0%) in the DM group and non-DM groups (p=0.410), respectively. All AS parameters (anterior chamber depth, volume, and angle) increased significantly postoperatively (p<0.001). Multivariate linear regression analysis showed that higher preoperative IOP was significantly associated with IOP reduction at 6-month follow-up (p<0.05). Conclusion. Nonglaucomatous eyes with open-angles from both type 2 diabetic and nondiabetic patients experienced similar AS changes and IOP reductions following uneventful phacoemulsification, and this IOP-lowering effect was strongly correlated with preoperative IOP.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10