Control of Allergic Rhinitis and Asthma Test for Children (CARATKids) Validation in Brazil and cutoff values

• Type: Article in International Scientific Journal
• Date: 2017

Authors

Amaral, R (Author) Other; Carneiro, AC (Author) Other; Wandalsen, G (Author) Other; Fonseca, J (Author) FMUP; Sole, D (Author) Other

Journal

Title: Annals of Allergy, Asthma and Immunology

Vol. 118

Pages: 551-+

ISSN: 1081-1206

Publisher: American College of Allergy, Asthma, & Immunology

Indexing

ISI Web of Knowledge - 15 Citations

Scopus - 17 Citations

Other information

Authenticus ID: P-00M-VEZ

DOI: 10.1016/j.anai.2017.02.007

Abstract (EN): Background: The Control of Allergic Rhinitis and Asthma Test for Children (CARATKids) assesses asthma and allergic rhinitis control in children younger than 12 years. Objective: To validate the Brazilian Portuguese version of the CARATKids and to define the cutoff values for identifying uncontrolled disease. Methods: Children aged 6 to 12 years with asthma and allergic rhinitis were studied (n = 102). CAR-ATKids, childhood Asthma Control Test (cACT), total nasal symptom score (TNSS), and visual analog scale (VAS) scores were obtained at baseline and after 4 to 6 weeks. Internal consistency, test-retest reliability, responsiveness, and validity of the Brazilian CARATKids were assessed according to the Consensus-based Standards for the Selection of Health Measurements Instruments checklist. The minimal clinically important difference (MCID) was evaluated using distribution and anchor methods. Spearman correlations were used to compare CARATKids scores with external measures of control. Receiver operating characteristic curve analysis was performed to establish cutoff values. Results: Fifty children completed both visits. The Cronbach a and intraclass correlation coefficient of CARATKids were 0.81 and 0.85, respectively. The Guyatt responsiveness index was -1.34, and within-patient change in clinically unstable patients (n = 31) was significant (P = .02). As for cross-sectional and longitudinal validity, correlation coefficients ranged from 0.58 to 0.77 (P<.001) and 0.30 to 0.57 (P<.05), respectively. The estimated MCID for CARATKids was 3. The optimal cutoffs (sensitivity and specificity) to exclude uncontrolled and controlled disease were 3 or less (97% and 67%) and 6 or greater (56% and 96%), respectively. Conclusion: CARATKids is a reliable and valid tool to assess asthma and allergic rhinitis control in Brazilian children. A score of 6 or higher on CARATKids identifies uncontrolled disease, and a score of 3 or lower excludes poor disease control.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8