Eligibility for Pre-exposure Prophylaxis According to Different Guidelines in a Cohort of HIV-Negative Men Who Have Sex with Men in Lisbon, Portugal

• Type: Article in International Scientific Journal
• Date: 2020

Authors

Meireles, P (Author) Other; Plankey, M (Author) Other; Rocha, M (Author) Other; Rojas, J (Author) Other; Brito, J (Author) Other; Barros H (Author) FMUP

Journal

Title: Sexuality Research and Social Policy

Vol. 17

Pages: 688-699

ISSN: 1868-9884

Publisher: Springer

Indexing

ISI Web of Knowledge - 3 Citations

Scopus - 4 Citations

Other information

Authenticus ID: P-00R-K3K

DOI: 10.1007/s13178-019-00426-9

Abstract (EN): Defining eligibility for preexposure prophylaxis (PrEP) is key to measuring the degree of PrEP implementation. While the clinical exclusion criteria are identical across different guidelines, definitions of substantial HIV risk are not. In this study, we aimed to estimate the proportion of men who have sex with men (MSM) being tested at a community-based voluntary human immunodeficiency virus (HIV) counseling and testing center in Lisbon that would be eligible for PrEP according to guidelines from the World Health Organization (WHO), the US Public Health Service and Centers for Disease Control and Prevention (US-CDC), the European AIDS Clinical Society (EACS), and the Portuguese National Health Service (PNHS). We used baseline data from 3392 HIV-negative MSM with valid information on eligibility for PrEP enrolled in the Portuguese Lisbon Cohort of MSM-an observational study designed as an open prospective, noninterval cohort-between March 2014 and March 2018. At baseline, the proportion of MSM eligible for PrEP was 67.7% according to the US-CDC, 60.6% according to the PNHS guidelines, 58.9% according to the WHO, and 46.5% according to the EACS guidelines. The most frequently met criteria were those related to condomless anal intercourse. In conclusion, in the same population, the proportion of men eligible for PrEP differed by guideline, ranging from 46.5% to 67.7%, though if they all seem to include the same well-known predictors of HIV seroconversion.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 12