Seasonality of cardiovascular risk factors: an analysis including over 230 000 participants in 15 countries

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Marti Soler, H (Author) Other; Gubelmann, C (Author) Other; Aeschbacher, S (Author) Other; Alves, L (Author) FMUP; Bobak, M (Author) Other; Bongard, V (Author) Other; Clays, E (Author) Other; de Gaetano, G (Author) Other; Di Castelnuovo, A (Author) Other; Elosua, R (Author) Other; Ferrieres, J (Author) Other; Guessous, I (Author) Other; Igland, J (Author) Other; Jorgensen, T (Author) Other; Nikitin, Y (Author) Other; O'Doherty, MG (Author) Other; Palmieri, L (Author) Other; Ramos, R (Author) Other; Simons, J (Author) Other; Sulo, G (Author) Other; Vanuzzo, D (Author) Other; Vila, J (Author) Other; Barros H (Author) FMUP; Borglykke, A (Author) Other; Conen, D (Author) Other; De Bacquer, D (Author) Other; Donfrancesco, C (Author) Other; Gaspoz, JM (Author) Other; Giampaoli, S (Author) Other; Giles, GG (Author) Other; Iacoviello, L (Author) Other; Kee, F (Author) Other; Kubinova, R (Author) Other; Malyutina, S (Author) Other; Marrugat, J (Author) Other; Prescott, E (Author) Other; Ruidavets, JB (Author) Other; Scragg, R (Author) Other; Simons, LA (Author) Other; Tamosiunas, A (Author) Other; Tell, GS (Author) Other; Vollenweider, P (Author) Other; Marques Vidal, P (Author) Other

Journal

Title: Heart

Vol. 100

Pages: 1517-1523

ISSN: 1355-6037

Publisher: BMJ PUBLISHING GROUP

Indexing

ISI Web of Knowledge - 93 Citations

Scopus - 97 Citations

Other information

Authenticus ID: P-009-V1N

DOI: 10.1136/heartjnl-2014-305623

Abstract (EN): Objective To assess the seasonality of cardiovascular risk factors (CVRF) in a large set of population-based studies. Methods Cross-sectional data from 24 population-based studies from 15 countries, with a total sample size of 237 979 subjects. CVRFs included Body Mass Index (BMI) and waist circumference; systolic (SBP) and diastolic (DBP) blood pressure; total, high (HDL) and low (LDL) density lipoprotein cholesterol; triglycerides and glucose levels. Within each study, all data were adjusted for age, gender and current smoking. For blood pressure, lipids and glucose levels, further adjustments on BMI and drug treatment were performed. Results In the Northern and Southern Hemispheres, CVRFs levels tended to be higher in winter and lower in summer months. These patterns were observed for most studies. In the Northern Hemisphere, the estimated seasonal variations were 0.26 kg/m(2) for BMI, 0.6 cm for waist circumference, 2.9 mm Hg for SBP, 1.4 mm Hg for DBP, 0.02 mmol/L for triglycerides, 0.10 mmol/L for total cholesterol, 0.01 mmol/L for HDL cholesterol, 0.11 mmol/L for LDL cholesterol, and 0.07 mmol/L for glycaemia. Similar results were obtained when the analysis was restricted to studies collecting fasting blood samples. Similar seasonal variations were found for most CVRFs in the Southern Hemisphere, with the exception of waist circumference, HDL, and LDL cholesterol. Conclusions CVRFs show a seasonal pattern characterised by higher levels in winter, and lower levels in summer. This pattern could contribute to the seasonality of CV mortality.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7