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Bariatric Surgery Impact on Cardiovascular Risk Factors: Is Age a Factor to Consider?

Title
Bariatric Surgery Impact on Cardiovascular Risk Factors: Is Age a Factor to Consider?
Type
Article in International Scientific Journal
Year
2020
Authors
Mendonça, F
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Silva, MM
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Salazar, D
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Correia, Flora
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Pedro, J
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Guerreiro, V
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Viana, S
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Neves, JS
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Belo, S
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Varela, A
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Freitas, P
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Carvalho, Davide
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FMUP
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Journal
Title: Obesity FactsImported from Authenticus Search for Journal Publications
Pages: [1-8]
ISSN: 1662-4025
Publisher: Karger
Scientific classification
CORDIS: Health sciences
FOS: Medical and Health sciences
Other information
Authenticus ID: P-00T-70K
Abstract (EN): Introduction: Despite the abundance of data addressing the influence of patient's age on surgery-related complications, its impact on cardiometabolic outcomes following bariatric surgery has been overlooked. Methods: Retrospective unicentric study of 1,728 obese patients who underwent bariatric surgery between January 2010 and June 2015. Patients were divided in 3 age groups, according to their age at surgery: ?40 (n = 751), 40-59 (n = 879), and ¿60 years (n = 98). Parameters with cardiometabolic impact, such as body anthropometric measures, lipid profile, and glycemic status, before and 24 months after surgery, were compared between these groups. A multiple linear regression was performed, adjusting differences between groups for sex, surgery type, and body mass index variation. Results: The group ?40 years presented more weight loss (-35.4 ± 9.0 kg, p ? 0.001), greater BMI reduction (-15.8 ± 6.1 kg/m2, p ? 0.001), and larger changes in waist (-34 ± 13.8 cm, p ? 0.001) and hip circumferences (-28.7 ± 11.9 cm, p ? 0.05). The group of ¿60 years presented the heaviest reduction in fasting glucose (-17.7 ± 32.8 mg/dL, p ? 0.001) and HbA1c (0.7 ± 1.0, p ? 0.001), and also had a tendency to have the biggest changes in systolic blood pressure (-14.7 ± 18.7 mm Hg, p = 0.071). Conclusion: Patients with ¿60 years benefit the most from bariatric surgery regarding cardiometabolic parameters, presenting heavier reductions in fasting glucose, as well as HbA1c and a tendency towards a higher decrease in systolic blood pressure. No clinically significant differences in lipid profile were observed between groups. © 2020
Language: English
Type (Professor's evaluation): Scientific
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