Biodegradation of antibiotics: The new resistance determinants ¿ part II

• Type: Another Publication in an International Scientific Journal
• Date: 2020

Authors

Ana C. Reis (Author) Other; Boris A. Kolvenbach (Author) Other; Olga C. Nunes (Author) FEUP; Philippe F. X. Corvini (Author) Other

Journal

Title: New Biotechnology

Vol. 54

Pages: 13-27

ISSN: 1871-6784

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 11 Citations

Other information

Authenticus ID: P-00Q-ZKD

DOI: 10.1016/j.nbt.2019.08.003

Abstract (EN): Antibiotic residues are widespread in the environment and their presence is known to contribute to the propagation of antibiotic resistance. Nevertheless, knowledge on processes involved in their degradation is scattered. This second part of a two part review aims at compiling knowledge on the (bio-) degradation of antibiotics, focusing on ß-lactams, macrolides, quinolones and ionophores, as well as some less common classes. Detailed metabolic and molecular aspects are discussed, as well as the role of antibiotic degraders in natural microbial communities. This exercise led to the conclusion that among the classes analyzed, the majority of antibiotics are prone to microbial cleavage or transformation. © 2019

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 15