Hydroxyapatite and Bioglass pellets, production process and applications of thereof, Worldwide Application

• Type: Patent
• Date: 2008

Authors

José Domingos da Silva Santos (Author) FEUP; M. A. Lopes (Author) FEUP; M. A. Silva (Author) Other

Patent

No. WO2010/021559

Scope: International

Scientific classification

FOS: Engineering and technology > Medical engineering

Other information

Abstract (EN): “Hydroxyapatite and bioglass-based pellets, production process and applications of thereof” The present invention refers to hydroxyapatite and bioglass-based pellets of homogeneous size and spherical shape, whose interconnective porous structure, in the micrometer range, allows for an enhanced osteoconductivity and osteointegration, with specific application as a synthetic bone graft and to the respective production process. The production process is based on the pharmaceutical technology of extrusion and spheronization employing a porogenic agent and applying a sinterization stage in the presence of a vitreous liquid phase, which reverts on behalf of a higher reproducibility, superior yield and greater production capacity. Therefore, the present invention is destined to the production of hydroxyapatite and bioglass-based pellets with applications in osteoregenerative medicine, particularly in the fields of orthopaedic surgery, maxillofacial surgery, dental surgery, implantology and as tissue engineering scaffolds.

Language: English

Type (Professor's evaluation): Scientific

Reference: PCT/PT2008/000032

No. of pages: 29