Cardiac morbidity in monochorionic twins

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Costa Castro, T (Author) Other; matias, a (Author) FMUP

Journal

Title: Diagnostico Prenatal

Vol. 25

Pages: 48-52

ISSN: 2173-4127

Publisher: Elsevier Doyma

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-008-PN3

DOI: 10.1016/j.diapre.2013.09.002

Abstract (EN): Twin pregnancies are at increased risk of complications and adverse outcome compared to singletons. A significant contribution to higher morbidity and mortality seen in monochorionic twins is made by cardiac complications. Abnormal cardiac development in monochorionic pregnancies can be divided into primary structural cardiac lesions (structural cardiac anomalies unrelated to the existence of TTTS) and acquired cardiac lesions (any cardiac anomaly considered to be associated with TTTS). The etiology of primary structural congenital heart disease in these twins is poorly understood. Both environmental and genetic factors influence this figure. Acquired cardiac lesions are the consequence of hemodynamic anomalies which can occur as a result of TTTS. These cardiac anomalies are present primarily in recipient twin and include biventricular hypertrophy and diastolic dysfunction as well as right ventricular outflow tract obstruction and pulmonic stenosis. This review will focus on anomalies of cardiac development in monochorionic twin pregnancies.

Language: English

Type (Professor's evaluation): Scientific