Longitudinal evaluation of computerized cardiotocographic parameters throughout pregnancy in normal fetuses: a prospective cohort study

• Type: Article in International Scientific Journal
• Date: 2016

Authors

Amorim Costa, C (Author) FMUP; Cristina Costa Santos (Author) FMUP; Diogo Ayres de Campos (Author) FMUP; Joao Bernardes (Author) FMUP

Journal

Title: Acta Obstetricia et Gynecologica Scandinavica

Vol. 95

Pages: 1143-1152

ISSN: 0001-6349

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 21 Citations

Scopus - 23 Citations

Other information

Authenticus ID: P-00K-XJM

DOI: 10.1111/aogs.12932

Abstract (EN): Introduction. The longitudinal cardiotocographic (CTG) changes throughout pregnancy in normal fetuses have never been fully described. We aimed at characterizing the evolution of CTG parameters in healthy fetuses, from 24 to 41 weeks of gestation. Material and methods. A prospective cohort study was conducted in singleton fetuses without structural abnormalities on second-trimester ultrasound. At least one CTG was performed in each of the following intervals: 24-26 weeks(+6d), 27-29 weeks(+6d), 30-32 weeks(+6d), 33-35 weeks(+6d), 36-38 weeks(+6d) and >= 39 weeks; tracings were analyzed by the OMNIVIEW-SISPORTO 3.6 system. Cases of preterm delivery, fetal death, birthweight under the 10th percentile, low five-minute Apgar, umbilical artery acidemia or neonatal intensive care unit admission were subsequently excluded. Results. A total of 1049 eligible tracings were obtained from 145 fetuses. There was a significant increase over time in average long-term variability (LTV), average short-term variability (STV), number of accelerations and uterine contractions. Conversely, fetal heart rate (FHR) baseline and number of decelerations decreased. A high inter-fetal variability was observed, but there was considerable intra-fetal consistency. Fetuses showing a marked decrease in FHR baseline and those with a marked increase in average LTV had a significantly lower birthweight. Cesarean section rate was significantly higher in cases with a decrease in average STV throughout gestation. Conclusions. This prospective longitudinal study shows an evolution in computerized CTG parameters during pregnancy, indicating the need to adapt interpretation criteria based on gestational age. The high inter-fetal variability and considerable intra-fetal consistency suggests the possible value of using each fetus as its own reference in serial assessments.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10