Self-expandable metal stents are a valid option in long-term survivors of advanced esophageal cancer

• Type: Article in International Scientific Journal
• Date: 2018

Authors

Rodrigues Pinto, E (Author) Other; Pereira, P (Author) Other; Baron, TH (Author) Other; Macedo G (Author) FMUP

Journal

Title: Revista Espanola de Enfermedades Digestivas

Vol. 110

Pages: 500-504

ISSN: 1130-0108

Publisher: Aran Ediciones SA

Indexing

ISI Web of Knowledge - 5 Citations

Scopus - 5 Citations

Other information

Authenticus ID: P-00P-DVK

DOI: 10.17235/reed.2018.5323/2017

Abstract (EN): Background: self-expandable metal stents are often used for the palliative treatment of dysphagia in patients with advanced esophageal cancer and an anticipated limited survival. Due to previous reports of a high rate of adverse event when used long-term, concerns have been raised with regard to the use of self-expandable metal stents in patients with a longer survival. Aim: assess the role of esophageal self-expandable metal stents in patients with advanced esophageal cancer that have survived longer than six months. Methods: retrospective study of patients with advanced esophageal cancer with a self-expandable metal stent and a stent placement time greater than six months. Results: forty-two patients were followed up for 298 days. There was a clinical improvement in all patients. However, 59% of patients experienced an adverse event. The median stent patency was 236 days. Endoscopic management was attempted in all self-expandable metal related adverse events, with a clinical success rate of 100%. However, the previously treated adverse event recurred in seven patients. Multivariate analysis showed that strictures that were traversable with an ultrathin gastroscope were associated with a higher risk of adverse events (p = 0.035). Conclusions: long-term esophageal stenting in patients with advanced esophageal cancer is associated with a high prevalence of adverse events without an impact on mortality; most cases can be managed endoscopically.

Language: English

Type (Professor's evaluation): Dissemination

No. of pages: 5