Treatment of chronic hepatitis C in liver transport patients [Terapêutica da hepatite C no transplante hepático]

• Type: Article in International Scientific Journal
• Date: 2000

Authors

Macedo G (Author) Other; Maia, JC (Author) Other; Gomes, A (Author) Other; Teixeira, A (Author) Other; Ribeiro, T (Author) Other

Journal

Title: Arquivos de Medicina

Vol. 14 No. 1

Pages: 156-160

ISSN: 0871-3413

Publisher: A E F M U P, Alameda prof. H. Montiero

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-008-Q54

Abstract (EN): Although graft reinfection with Hepatitis C (HCV) virus, after liver transplantation, is the rule, the clinical consequences of reinfection are highly variable. A subset of transplanted patients with recurrent hepatitis C develops severe graft injury, but there has been no consistent correlation between viral or host factors that might predict recurrence or the progression of liver injury. Efficient prophylaxis has not been achieved yet and anti-viral treatment, although promising, did not achieve sustained results that might promote a more widespread use. Medium-term survival is good but there exists some concern with regard to the long-term outcome, and the factors that might influence the development of end-stage liver disease. Sustained combination treatment may prove to be the only strategy to reduce morbidity and mortality in the ever growing number of immunossupressed HCV reinfected patients.

Language: Portuguese

Type (Professor's evaluation): Scientific