Non alcoholic fatty liver disease [Doença hepática esteatósica não alcoólica]

• Type: Another Publication in an International Scientific Journal
• Date: 2004

Authors

Lopes, S (Author) Other; Macedo G (Author) Other

Journal

Title: Arquivos de Medicina

Vol. 18

Initial page: 297

ISSN: 0871-3413

Publisher: A E F M U P, Alameda prof. H. Montiero

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-007-E1H

Abstract (EN): Non alcoholic fatty liver disease (NAFLD) is a clinicopathologic syndrome with increasing significance. It refers to a wide spectrum of hepatic lesions, ranging from steatosis, to steatohepatitis, fibrosis and cirrhosis. It was originally described in obese, diabetic, middle-aged women, who did not drink alcohol, but whose hepatic histology was similar to alcoholic liver disease. This typical patient profile has been expanded and is now recognized to occur in normal weight men without overt abnormalities in carbohydrate metabolism. It is considered one of the most common causes of liver enzymes elevations and it may potentiate liver damage induced by other hepatotoxic agents. There are no specific diagnostic tools, and sometimes the diagnosis is made presumptively, in an obese patient, with elevated transaminases, without any other recognized cause of liver disease. A definitive diagnosis is achieved with liver biopsy. Although initially considered a benign disease it is now known that it can progress to fibrosis, cirrhosis and end-stage liver disease. ©ArquiMed, 2004.

Language: Portuguese

Type (Professor's evaluation): Scientific