HVI and HVII sequence polymorphisms of the human mtDNA in the North of Portugal: Population data and maternal lineages

• Type: Article in International Scientific Journal
• Date: 2006

Authors

Laura Cainé (Collaborator) FMUP

Journal

Title: International Congress Series

Vol. 1288

Pages: 133-135

ISSN: 0531-5131

Publisher: Elsevier B.V.

Indexing

Scopus - 1 Citation

Other information

Authenticus ID: P-007-GYH

DOI: 10.1016/j.ics.2005.10.055

Abstract (EN): We have analysed the sequence polymorphisms of the hypervariable segments I and II (HVI and HVII) of the human mitochondrial DNA (mtDNA) in the population of North of Portugal. The aim of this study was to create a population database for HVI and HVII regions and to analyse these two segments in maternal relatives. For the population data, the HVI and HVII segments were analysed in 142 unrelated and healthy individuals, chosen randomly, from the North of Portugal. For the maternal lineages analysis, these two segments were studied in 24 sets of families from that region of Portugal. The sequence polymorphisms of the HVI and HVII were determined by polymerase chain reaction (PCR) and direct sequencing.

Language: English

Type (Professor's evaluation): Scientific