Enantiomeric ratios: Why so many notations?

• Type: Another Publication in an International Scientific Journal
• Date: 2018

Authors

M E Tiritan (Author) FFUP; Carla Fernandes (Author) FFUP; Maia, AS (Author) Other; Pinto, M (Author) Other; Cass, QB (Author) Other

Journal

Title: Journal of Chromatography A

Vol. 1569

Pages: 1-7

ISSN: 0021-9673

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 21 Citations

Scopus - 22 Citations

Other information

Authenticus ID: P-00P-1XE

DOI: 10.1016/j.chroma.2018.07.039

Abstract (EN): The correct quantification of enantiomers is pivotal in a variety of fields, such as pharmacokinetic studies, enantioselective syntheses, chemical characterization of natural products, authentication of fragrance and food, biodegradation behavior, accurate evaluation of environmental risk, and it can also provide information for sentencing guidance in forensic field. Enantioselective chromatography is the first choice to assess the composition of an enantiomeric mixture. Different notations have been used to express the measured enantiomeric ratios, which compromise the results and represent a challenge for data comparison. This manuscript critically discusses the currently used notations and exemplifies with applications in different fields indicating the advantages and disadvantages of one of the adopted systems. In order to simplify the notations, the use of enantiomeric ratio (e.r.%) as standardization for nonchiroptical methods is proposed.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7