Chiral Stationary Phases for Liquid Chromatography: Recent Developments

• Type: Another Publication in an International Scientific Journal
• Date: 2019

Authors

Teixeira, J (Author) Other; M E Tiritan (Author) FFUP; Pinto, MMM (Author) Other; Carla Fernandes (Author) FFUP

Journal

Title: Molecules

Vol. 24

Final page: 865

ISSN: 1420-3049

Publisher: MDPI

Indexing

ISI Web of Knowledge - 113 Citations

Scopus - 122 Citations

Other information

Authenticus ID: P-00Q-B3K

DOI: 10.3390/molecules24050865

Abstract (EN): The planning and development of new chiral stationary phases (CSPs) for liquid chromatography (LC) are considered as continuous and evolutionary issues since the introduction of the first CSP in 1938. The main objectives of the development strategies were to attempt the improvement of the chromatographic enantioresolution performance of the CSPs as well as enlarge their versatility and range of applications. Additionally, the transition to ultra-high-performance LC were underscored. The most recent strategies have comprised the introduction of new chiral selectors, the use of new materials as chromatographic supports or the reduction of its particle size, and the application of different synthetic approaches for preparation of CSPs. This review gathered the most recent developments associated to the different types of CSPs providing an overview of the relevant advances that are arising on LC.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 38