Antithrombotics from the Sea: Polysaccharides and Beyond

• Type: Another Publication in an International Scientific Journal
• Date: 2019

Authors

Carvalhal, F (Author) Other; Cristelo, RR (Author) Other; Resende, DISP (Author) Other; Pinto, MMM (Author) Other; Emilia Sousa (Author) FFUP; Marta Correia da Silva (Author) FFUP

Journal

Title: Marine Drugs

Vol. 17

Final page: 170

ISSN: 1660-3397

Publisher: MDPI

Indexing

ISI Web of Knowledge - 40 Citations

Scopus - 50 Citations

Other information

Authenticus ID: P-00Q-CTK

DOI: 10.3390/md17030170

Abstract (EN): Marine organisms exhibit some advantages as a renewable source of potential drugs, far beyond chemotherapics. Particularly, the number of marine natural products with antithrombotic activity has increased in the last few years, and reports show a wide diversity in scaffolds, beyond the polysaccharide framework. While there are several reviews highlighting the anticoagulant and antithrombotic activities of marine-derived sulfated polysaccharides, reports including other molecules are sparse. Therefore, the present paper provides an update of the recent progress in marine-derived sulfated polysaccharides and quotes other scaffolds that are being considered for investigation due to their antithrombotic effect.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 31