Low affinity Fc receptor for IgE-CD23 [O RECEPTOR CELULAR DE BAIXA AFINIDADE PARA A IMUNOGLOBULINA E-CD23]

• Type: Another Publication in an International Scientific Journal
• Date: 1994

Authors

Cuesta, C (Author) Other; Delgado, L (Author) FMUP; Vaz, M (Author) Other

Journal

Title: Arquivos de Medicina

Vol. 8 No. 4

Pages: 40-44

ISSN: 0871-3413

Publisher: A E F M U P, Alameda prof. H. Montiero

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-007-664

Abstract (EN): CD23 is an unique protein functioning as a low affinity Fc receptor for IgE in eosinophils, macrophages and platelets, that mediates cellular cytotoxicity, phagocytosis, adhesion and antigen presentation. As other members of the ubiquitous mammalian C-type lectins, soluble forms of this molecule - sCD23 - have been described, and new findings suggest its functional role in the immune and inflammatory response. In this article we summarize some of the recently described functions of CD23 and its soluble fragments, and the clinical implications and perspectives for the study of this multifunctional molecule in several human diseases.

Language: Portuguese

Type (Professor's evaluation): Scientific