Design and applications of cyclic peptides

• Type: Chapter or Part of a Book
• Date: 2017-03-01

Authors

Bastos, M (Author) FCUP

Book

Title: Peptide Applications in Biomedicine, Biotechnology and Bioengineering

Pages: 87-129

ISBN: 9780081007426; 9780081007365

Indexing

Scopus - 24 Citations

Other information

Authenticus ID: P-00N-JNB

DOI: 10.1016/b978-0-08-100736-5.00004-1

Abstract (EN): Cyclic peptides (CPs) belong to an interesting class of peptides that have been widely studied over the past decades. This class of peptides has been applied in different fields, such as the pharmaceutical industry (due to their antibacterial or antitumor activity), agricultural applications (as fungicides), diagnostics, and vaccines.One of the main sources of inspiration for designing CPs is Nature itself. Different approaches to the design of CPs have been used, depending on the application for which they are prepared. Indeed, understanding the mechanisms of action of CPs will contribute to an improved rational design of new CPs with different applications. In this chapter, we show the presence of the CPs and their derivatives in Nature, and provide its accepted classification. Methods for designing new CPs as well as the respective experimental approaches are also discussed. Finally, some of the main important applications of these systems are reviewed.

Language: English

Type (Professor's evaluation): Scientific