Rapid Flow Cytometry Test for Identification of Different Carbapenemases in Enterobacteriaceae

• Type: Article in International Scientific Journal
• Date: 2016

Authors

Silva, AP (Author) Other; Faria Ramos, I (Author) Other; Ricardo, E (Author) Other; miranda, im (Author) FMUP; Espinar, MJ (Author) Other; Sofia Costa de Oliveira (Author) FMUP; Canton, R (Author) Other; rodrigues, ag (Author) FMUP; pina-vaz, c (Author) FMUP

Journal

Title: Antimicrobial Agents and Chemotherapy

Vol. 60

Pages: 3824-3826

ISSN: 0066-4804

Publisher: American Society for Microbiology

Indexing

ISI Web of Knowledge - 11 Citations

Scopus - 12 Citations

Other information

Authenticus ID: P-00K-HT0

DOI: 10.1128/aac.02947-15

Abstract (EN): A flow cytometry test was developed to identify carbapenemase production by Enterobacteriaceae and to discriminate between the different types of carbapenemases (classes A, B, and D). It is based on the detection of meropenem activity against bacteria, coupled with different carbapenemase inhibitors, which is assessed by flow cytometry. It represents a convenient, fast, and reliable approach (100% sensitivity and 100% specificity) for the detection and characterization of different carbapenemases.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3