Malassezia infections with systemic involvement: Figures and facts

• Type: Article in International Scientific Journal
• Date: 2018

Authors

Pedrosa, AF (Author) Other; Carmen Silva (Author) FMUP; rodrigues, ag (Author) FMUP

Journal

Title: Journal of Dermatology

Vol. 45

Pages: 1278-1282

ISSN: 0385-2407

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 23 Citations

Scopus - 29 Citations

Other information

Authenticus ID: P-00P-PX1

DOI: 10.1111/1346-8138.14653

Abstract (EN): Malassezia are lipophilic and commensal yeasts capable of inducing skin disease among susceptible hosts. However, severely immunocompromised patients and preterm infants admitted to intensive care units are particularly at risk of developing Malassezia systemic infections. Patients often have central venous catheters which are usually the portal of entry for colonization and infection. In addition to the clinically non-specific findings, a delay in the laboratorial diagnosis may occur as there is often the need to add lipid supplementation to culture in order to support these organisms' growth. Herein, we report three unrelated cases of Malassezia bloodstream infection at a university hospital during a 2-year period, followed by a discussion of the clinical results and comparison with the most recently available published data on epidemiology and risk factors, pathogenesis, diagnosis, susceptibility profile and treatment.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5