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Acute generalized exanthematous pustulosis to amoxicillin associated with parvovirus B19 reactivation

Title
Acute generalized exanthematous pustulosis to amoxicillin associated with parvovirus B19 reactivation
Type
Article in International Scientific Journal
Year
2012
Authors
Calistru, AM
(Author)
Other
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Carmen Silva
(Author)
FMUP
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Ana Cunha
(Author)
FMUP
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Bettencourt, H
(Author)
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Azevedo, F
(Author)
Other
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Journal
Vol. 31
Pages: 258-261
ISSN: 1556-9527
Publisher: Taylor & Francis
Other information
Authenticus ID: P-002-6K4
Abstract (EN): We report the case of a 22-year-old male patient with 2 episodes, 4 months apart, of acute generalized exanthematous pustulosis (AGEP) associated with oral intake of amoxicillin and simultaneous reactivation of parvovirus B19 infection proven by positive polymerase chain reaction test in the skin fragment and blood sample and elevation of the IgG antibodies titer. To our knowledge, this is the first report of AGEP resulting from the interaction between drug hypersensitivity and the reactivation of parvovirus B19. A combination of an immunological reaction to the drug and virus infection could be responsible for the clinical picture.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 4
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