Tuberculosis in a child presenting as asymptomatic oropharyngeal and laryngeal lesions

• Type: Article in International Scientific Journal
• Date: 2003

Authors

magina, s (Author) FMUP; Carmen Silva (Author) FMUP; Resende, C (Author) Other; Azevedo, F (Author) Other; Amado, F (Author) Other; Cardoso, V (Author) Other; Almeida, F (Author) Other; Mesquita Guimaraes, J (Author) Other

Journal

Title: Pediatric Dermatology

Vol. 20

Pages: 429-431

ISSN: 0736-8046

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 6 Citations

Scopus - 9 Citations

Other information

Authenticus ID: P-000-FEA

DOI: 10.1046/j.1525-1470.2003.20513.x

Abstract (EN): We describe an 11-year-old boy who had several, asymptomatic, erythematous papules in the oropharynx and larynx with recent onset, two cervical lymphadenopathies, and a painless, erythematous plaque on the right wrist with a 2.5-year history of slow growth. Histologic examination of the mucocutaneous lesions revealed a submucous infiltrate of lymphocytes and Langhans giant cells in the papules and granulomatous dermatitis in the plaque. The cervical lymph node was biopsied and on the surgical scar, an erythematous, nodular lesion developed. A biopsy specimen of this lesion showed tuberculoid granulomas with prominent caseation necrosis, and culture was positive for Mycobacterium tuberculosis. The Mantoux test was strongly positive with a vesicular response. A diagnosis of mucocutaneous lupus vulgaris and scrofuloderma secondary to cervical tuberculous lymphadenitis was made. Two months after initiation of antituberculosis therapy there was a complete resolution of mucous lesions and healing with atrophic scars on the neck and wrist. This is a rare presentation in the literature and reminds clinicians that tuberculosis should be kept in mind in the differential diagnosis of oral cavity lesions.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3