Phylogeny of the Teashirt-related Zinc Finger (tshz) Gene Family and Analysis of the Developmental Expression of tshz2 and tshz3b in the Zebrafish

• Type: Article in International Scientific Journal
• Date: 2010

Authors

Santos, JS (Author) Other; Nuno A Fonseca (Author) Other; Cristina Vieira (Author) Other; Vieira, J (Author) FEUP; Casares, F (Author) Other

Journal

Title: Developmental Dynamics

Vol. 239

Pages: 1010-1018

ISSN: 1058-8388

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 13 Citations

Scopus - 13 Citations

Other information

Authenticus ID: P-003-8HC

DOI: 10.1002/dvdy.22228

Abstract (EN): The tshz genes comprise a family of evolutionarily conserved transcription factors. However, despite the major role played by Drosophila tsh during the development of the fruit fly, the expression and function of other tshz genes have been analyzed in a very limited set of organisms and, therefore, our current knowledge of these genes is still fragmentary. In this study, we perform detailed phylogenetic analyses of the tshz genes, identify the members of this gene family in zebrafish and describe the developmental expressions of two of them, tshz2 and tshz3b, and compare them with meis1, meis2.1, meis2.2, pax6a, and pax6b expression patterns. The expression patterns of these genes define a complex set of coexpression domains in the developing zebrafish brain where their gene products have the potential to interact. Developmental Dynamics 239:1010-1018, 2010. (C) 2010 Wiley-Liss, Inc.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9