High levels of nucleotide diversity in the European rabbit (Orydolagus cuniculus) SRY gene

• Type: Article in International Scientific Journal
• Date: 2005

Authors

Geraldes, A (Author) Other; Rogel Gaillard, C (Author) Other; ferrand, n (Author) FCUP

Journal

Title: Animal Genetics

Vol. 36

Pages: 349-351

ISSN: 0268-9146

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 32 Citations

Scopus - 33 Citations

Other information

Authenticus ID: P-000-1ZM

DOI: 10.1111/j.1365-2052.2005.01300.x

Abstract (EN): We have sequenced 2388 bp of the European rabbit sex determining region Y (SRY) gene. These data provide a 10-fold increase in the coverage of the Y chromosome in this species, including the entire open reading frame of the SRY, the polyadenylation signal, and two repetitive sequences in the 5'-region. A survey of 2021 bp of this gene in eight domestic breeds and four wild individuals revealed a total of nine single nucleotide polymorphisms and one indel, defining two deeply divergent lineages. The resulting estimation of nucleotide diversity (pi = 1.34 x 10(-3)) is very high when compared with other species, but no variability was detected among the domestic breeds. This study represents a first step in the characterization of the European rabbit Y chromosome and its variability. These sequences can be used in additional phylogeographical analyses of the European rabbit and other Leporid species, as well as in evolutionary studies of sex determination and the Y chromosome in wild species.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3