Emerging Viruses in the Felidae: Shifting Paradigms

• Type: Another Publication in an International Scientific Journal
• Date: 2012

Authors

O'Brien, SJ (Author) Other; Troyer, JL (Author) Other; Brown, MA (Author) Other; Johnson, WE (Author) Other; Agostinho Antunes (Author) FCUP; Roelke, ME (Author) Other; Pecon Slattery, J (Author) Other

Journal

Title: Viruses-Basel

Vol. 4

Pages: 236-257

ISSN: 1999-4915

Indexing

ISI Web of Knowledge - 36 Citations

Scopus - 40 Citations

Other information

Authenticus ID: P-002-DEH

DOI: 10.3390/v4020236

Abstract (EN): The domestic cat is afflicted with multiple viruses that serve as powerful models for human disease including cancers, SARS and HIV/AIDS. Cat viruses that cause these diseases have been studied for decades revealing detailed insight concerning transmission, virulence, origins and pathogenesis. Here we review recent genetic advances that have questioned traditional wisdom regarding the origins of virulent Feline infectious peritonitis (FIP) diseases, the pathogenic potential of Feline Immunodeficiency Virus (FIV) in wild non-domestic Felidae species, and the restriction of Feline Leukemia Virus (FeLV) mediated immune impairment to domestic cats rather than other Felidae species. The most recent interpretations indicate important new evolutionary conclusions implicating these deadly infectious agents in domestic and non-domestic felids.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 22