Miniaturized voltammetric cell for cathodic voltammetry making use of an agar membrane

• Type: Article in International Scientific Journal
• Date: 2018

Authors

Skalova, S (Author) Other; Goncalves, LM (Author) Other; Navratil, T (Author) Other; Barek, J (Author) Other; Rodrigues, JA (Author) FCUP; Vyskocil, V (Author) Other

Journal

The Journal is awaiting validation by the Administrative Services.

Title: JOURNAL OF ELECTROANALYTICAL CHEMISTRY

Vol. 821

Pages: 47-52

ISSN: 0022-0728

Indexing

ISI Web of Knowledge - 9 Citations

Scopus - 7 Citations

Other information

Authenticus ID: P-00P-079

DOI: 10.1016/j.jelechem.2017.12.073

Abstract (EN): Analysis of samples available in small volumes is an important challenge in analytical chemistry. Therefore, we have dealt with the development of a new miniaturized micro-volume voltammetric cell (MVVC) for the determination of reducible organic compounds in micro-volumes (20-50 mu L). The MVVC is composed of two compartments, a micro-volume compartment, where the analyte is present along with the working electrode, separated by means of an agar membrane (about 2 mm) from a large-volume compartment containing the supporting electrolyte and the counter and reference electrodes. This MVVC was tested by the determination of sodium anthraquione-2-sulfonate as a model substance for structurally similar anthraquinone-based anti-cancer drugs. Using differential pulse voltammetry at a polished silver solid amalgam electrode, the following analytical parameters were obtained: linear dynamic range from 1 mu mol L-1 to 1 mmol L-1, repeatability of 0.7% (on the concentration level 0.1 mmol L-1), and limit of detection of 0.15 mu mol L-1.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6