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A No-Reference Quality Metric for Retinal Vessel Tree Segmentation

Title
A No-Reference Quality Metric for Retinal Vessel Tree Segmentation
Type
Article in International Conference Proceedings Book
Year
2018
Authors
Adrian Galdran
(Author)
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Pedro Costa
(Author)
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Alessandro Bria
(Author)
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Teresa Araújo
(Author)
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Ana Maria Mendonça
(Author)
FEUP
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Aurélio Campilho
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Conference proceedings International
Pages: 82-90
21st International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI)
Granada, SPAIN, SEP 16-20, 2018
Other information
Authenticus ID: P-00P-KDD
Abstract (EN): Due to inevitable differences between the data used for training modern CAD systems and the data encountered when they are deployed in clinical scenarios, the ability to automatically assess the quality of predictions when no expert annotation is available can be critical. In this paper, we propose a new method for quality assessment of retinal vessel tree segmentations in the absence of a reference ground-truth. For this, we artificially degrade expert-annotated vessel map segmentations and then train a CNN to predict the similarity between the degraded images and their corresponding ground-truths. This similarity can be interpreted as a proxy to the quality of a segmentation. The proposed model can produce a visually meaningful quality score, effectively predicting the quality of a vessel tree segmentation in the absence of a manually segmented reference. We further demonstrate the usefulness of our approach by applying it to automatically find a threshold for soft probabilistic segmentations on a per-image basis. For an independent state-of-the-art unsupervised vessel segmentation technique, the thresholds selected by our approach lead to statistically significant improvements in F1-score (+2.67%) and Matthews Correlation Coefficient (+3.11%) over the thresholds derived from ROC analysis on the training set. The score is also shown to correlate strongly with F1 and MCC when a reference is available.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 9
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