Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

• Type: Another Publication in an International Scientific Journal
• Date: 2018

Authors

Diana Oliveira (Author) FEUP; Anabela Borges (Author) FEUP; Manuel Simões (Author) FEUP

Journal

Title: Toxins

Serial No. 6 Vol. 10 No. 252

Pages: 1-252

ISSN: 2072-6651

Publisher: MDPI

Indexing

ISI Web of Knowledge - 18 Citations

ISI Web of Science

Scopus - 241 Citations

Associated Projects

LEPABE - Laboratório de Engenharia de Processos, Ambiente, Biotecnologia e Energia

LEPABE-2-ECO-INNOVATION - LEPABE-2-ECO-INNOVATION

Other information

Authenticus ID: P-00P-0QE

DOI: 10.3390/toxins10060252

Abstract (EN): Staphylococcus aureus is a microorganism resident in the skin and nasal membranes with a dreadful pathogenic potential to cause a variety of community and hospital-acquired infections. The frequency of these infections is increasing and their treatment is becoming more difficult. The ability of S. aureus to form biofilms and the emergence of multidrug-resistant strains are the main reasons determining the challenge in dealing with these infections. S. aureus' infectious capacity and its success as a pathogen is related to the expression of virulence factors, among which the production of a wide variety of toxins is highlighted. For this reason, a better understanding of S. aureus toxins is needed to enable the development of new strategies to reduce their production and consequently improve therapeutic approaches. This review focuses on understanding the toxin-based pathogenesis of S. aureus and their role on infectious diseases.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 19