B-type natriuretic peptide is related to left ventricular mass in hypertensive patients but not in athletes

• Type: Article in International Scientific Journal
• Date: 2002

Authors

S Almeida (Author) FMUP; Azevedo A (Author) FMUP; Castro, A (Author) Other; Friões F (Author) FMUP; Freitas, J (Author) FMUP; Ferreira A (Author) FMUP; Bettencourt P (Author) FMUP

Journal

Title: Cardiology

Vol. 98

Pages: 113-115

ISSN: 0008-6312

Publisher: Karger

Indexing

ISI Web of Knowledge - 30 Citations

Scopus - 35 Citations

Other information

Authenticus ID: P-000-QXX

DOI: 10.1159/000066319

Abstract (EN): A positive correlation has been previously documented between B-type natriuretic peptide (BNP) levels and left ventricular mass index (LVMI) in hypertensive patients. We evaluated 8 cycling athletes, 8 healthy age-matched controls; 17 hypertensive patients and 7 age-matched controls. LVMI was significantly higher in athletes and hypertensive patients than in their controls. Plasma levels of BNP in hypertensive patients were significantly higher than in athletes and their age-matched controls. No significant difference was found between athletes and their controls. Cycling athletes had significantly larger LVMI than hypertensive patients and controls, without elevated BNP levels. These results suggest that BNP levels are elevated in patients with increased LVM due to hypertension but not in physiologically increased LVM. Whether elevated BNP levels in athletes is a sign of structural heart disease merits further investigation. Copyright (C) 2002 S. Karger AG, Basel.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3