Extending the reservoir of bla (IMP-5): the emerging pathogen Acinetobacter bereziniae

• Type: Article in International Scientific Journal
• Date: 2015

Authors

Grosso, F (Author) Other; Silva, L (Author) Other; Sousa, C (Author) Other; Ramos, H (Author) Other; Quinteira, S (Author) FCUP; Luisa Peixe (Author) FFUP

Journal

Title: Future Microbiology

Vol. 10

Pages: 1609-1613

ISSN: 1746-0913

Publisher: Future Medicine Ltd.

Indexing

ISI Web of Knowledge - 11 Citations

Scopus - 11 Citations

Other information

Authenticus ID: P-00G-TV8

DOI: 10.2217/fmb.15.88

Abstract (EN): Aim:Acinetobacter bereziniae clinical relevance is starting to be recognized; however, very few descriptions of its carbapenem resistance currently exist. Here we characterize two carbapenem-resistant A. bereziniae isolates. Materials & methods: Isolates were obtained from environmental and clinical samples. Carbapenemases were searched by phenotypic, biochemical and PCR assays. Clonality was studied by ApaI-PFGE and genetic location for carbapenemase genes were assessed by I-CeuI and S1 hybridizations. Results: Isolates were not clonally related but both produced the exclusively Portuguese' IMP-5, with the clinical isolate also producing an OXA-58. The carbapenemase genes were plasmid located. Conclusion: Our results emphasize the role of non-baumannii Acinetobacter species as important reservoirs of clinically relevant resistance genes that could also contribute to their emergence as nosocomial pathogens.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5